The use of systematic reviews to justify phase III ophthalmology trials: an analysis.

Trevor TorgersonSheridan EvansBradley S JohnsonMatt Vassar

Published in: Eye (London, England) (2020)

Less than one-quarter of phase III RCTs cited systematic reviews as justification for conducting the RCT. We believe placing a higher priority on justifying RCTs with systematic reviews would go a long way to minimizing research waste within ophthalmology.

Keyphrases

phase iii
systematic review
open label
meta analyses
clinical trial
artificial intelligence
double blind
phase ii
placebo controlled
heavy metals
randomized controlled trial
risk assessment
study protocol
municipal solid waste