Proteomic Associations of Adverse Outcomes in Human Heart Failure.
Marie-Joe DibMichael G LevinLei ZhaoAhmed DiabZhaoqing WangChristina EbertOday SalmanJoe David AzzoSushrima GanPayman ZamaniJordana B CohenDipender GillStephen BurgessLoukas ZagkosVanessa P M van EmpelArthur Mark RichardsRobert Neil DoughtyErnst R RietzschelKarl KammerhoffErika M KvikstadJoseph C MaranvillePeter H SchaferDietmar A SeiffertFrancisco Ramírez-ValleDavid A GordonChing-Pin ChangAli JavaheriDouglas L MannThomas P CappolaJulio Alonso ChirinosPublished in: Journal of the American Heart Association (2024)
This study implicates multiple novel proteins in HF and provides preliminary evidence of associations between genetically predicted plasma levels of 17 candidate proteins and the risk for adverse outcomes in human HF.