Impact of prior malignancies on outcome of colorectal cancer; revisiting clinical trial eligibility criteria.
Muneer J Al-HusseiniAnas M SaadHadeer H MohamedMohamad A AlkhayatMohamad Bassam SonbolOmar Abdel-RahmanPublished in: BMC cancer (2019)
A prior malignancy before CRC -in general- can be associated with worse clinical survival outcomes. These worse outcomes are not observed in stage IV CRC. Considering these results when including/excluding stage IV CRC patients with prior malignancies in clinical trials may play help improve their generalizability.