Cardiac CT vs Echocardiography for Intracardiac Thrombus Detection in Ischemic Stroke: A Systematic Review and Meta-Analysis of 43 Studies.
Sherief A GhozyMichael LiuKobeissi HassanAli MortezaeiMelika AmoukhtehAlzhraa S AbbasAdam Andrew DmytriwRamanathan KadirvelAlejandro A RabinsteinDavid F KallmesDeena NasrPublished in: Neurology (2024)
CCT demonstrates high sensitivity, specificity, and diagnostic odds ratios in detecting intracardiac thrombus compared with traditional echocardiography. Limitations include the lack of randomized controlled studies, and other cardioembolic sources of stroke such as valvular disease, cardiac function, and aortic arch disease were not examined in our analysis. Large-scale studies are warranted to further evaluate CCT as a promising alternative for identifying intracardiac thrombus and other sources of cardioembolic stroke.
Keyphrases
- atrial fibrillation
- left atrial appendage
- left ventricular
- computed tomography
- case control
- drinking water
- pulmonary hypertension
- open label
- magnetic resonance imaging
- oral anticoagulants
- heart failure
- randomized controlled trial
- contrast enhanced
- clinical trial
- positron emission tomography
- placebo controlled
- phase iii
- cerebral ischemia
- blood brain barrier
- study protocol
- subarachnoid hemorrhage
- data analysis