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Diabetes mellitus and periodontitis: Inflammatory response in orthodontic tooth movement.

Milton SantamariaLeonardo BagneEwerton ZaniboniMauro Pedrine SantamariaMaria Aparecida Neves JardiniMaíra FelonatoGláucia Maria Tech Dos SantosFernanda Aparecida Sampaio MendonçaMarcelo Augusto Marretto Esquisatto
Published in: Orthodontics & craniofacial research (2019)
Diabetes Mellitus modifies the inflammatory response. The increased expression of inflammatory markers IL-6, TNF-α and TGF-β1 in diabetic animals impairs neovasculogenesis and tissue reorganization during orthodontic tooth movement, which may be aggravated by periodontitis.
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