Combining information from genome-wide association and multi-tissue gene expression studies to elucidate factors underlying genetic variation for residual feed intake in Australian Angus cattle.
Sara de Las Heras-SaldanaSamuel A ClarkNaomi DuijvesteijnCedric GondroJulius H J van der WerfYizhou ChenPublished in: BMC genomics (2019)
Our results showed six QTL regions associated with RFI in a beef Angus population where five of these QTL contained genes that have expression associated with this trait. Therefore, here we show that integrating information from gene expression and GWAS studies can help to better understand the genetic mechanisms that determine variation in complex traits.