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Prediction of activity and specificity of CRISPR-Cpf1 using convolutional deep learning neural networks.

Jiesi LuoWei ChenLi XueBin Tang
Published in: BMC bioinformatics (2019)
DeepCpf1 can significantly improve the accuracy of Cpf1-based genome editing and facilitates the generation of optimized guide RNAs libraries.
Keyphrases
  • genome editing
  • neural network
  • crispr cas
  • deep learning
  • artificial intelligence
  • machine learning
  • structural basis
  • dna methylation
  • genome wide