Alterations in Homologous Recombination-Related Genes and Distinct Platinum Response in Metastatic Triple-Negative Breast Cancers: A Subgroup Analysis of the ProfiLER-01 Trial.
Elise BonnetVéronique HaddadStanislas QuesadaKim-Arthur BaffertAudrey Lardy-CléaudIsabelle TreilleuxDaniel PissalouxValéry AttignonQing WangAdrien BuissonPierre-Etienne HeudelThomas BachelotArmelle DufresneLauriane EberstPhilippe ToussaintValérie BonadonaChristine LassetAlain ViariEmilie SohierSandrine PaindavoineValérie CombaretDavid PérolIsabelle L Ray-CoquardJean Yves BlayOlivier TrédanPublished in: Journal of personalized medicine (2022)
, a more comprehensive evaluation of HRD should be considered in order to enlarge the selection of patients with mTNBC that could benefit from platinum-based chemotherapy.