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MR elastography identifies regions of extracellular matrix reorganization associated with shorter survival in glioblastoma patients.

Siri Fløgstad SvenssonSkarphedinn HalldorssonAnna LatyshevaElies Fuster-GarciaTrine HjørnevikJorunn Fraser-GreenRobin Anthony Birkeland BuggeJack GrinbandSverre HolmRalph SinkusEinar Osland Vik-MoKyrre Eeg Emblem
Published in: Neuro-oncology advances (2023)
MRE imaging of glioblastoma can provide noninvasive information on intratumoral heterogeneity. Regions of increased stiffness were associated with extracellular matrix reorganization. An expression signal associated with "stiff" biopsies correlated with shorter survival of glioblastoma patients.
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