Multiplex Analysis of CircRNAs from Plasma Extracellular Vesicle-Enriched Samples for the Detection of Early-Stage Non-Small Cell Lung Cancer.

Carlos Pedraz-ValduncielStavros GiannoukakosAna Giménez-CapitánDiogo FortunatoMartyna FilipskaJordi Bertran-AlamilloJillian Wilhelmina Paulina BrachtAna DrozdowskyjJoselyn ValarezoNatasa ZarovniAlberto Fernández-Hilario Michael HackenbergAndrés Aguilar-HernándezMiguel Ángel Molina-VilaRafael Rosell

Published in: Pharmaceutics (2022)

This study validates the use of the nCounter platform for multiplexed EV-circRNA expression studies in LC patient samples, allowing the development of prognostic signatures.

Keyphrases

early stage
high throughput
real time pcr
poor prognosis
case report
single cell
simultaneous determination
loop mediated isothermal amplification
squamous cell carcinoma
long non coding rna
label free
case control
high resolution
liquid chromatography
rectal cancer
sensitive detection