Genetic variability in 13q33 and 9q34 is linked to aggressiveness patterns and a higher risk of progression of non-muscle-invasive bladder cancer at the time of diagnosis.

Louis Lenfant Geraldine Cancel-TassinStéphane GazutEva CompératMorgan RouprêtOlivier Cussenot

Published in: BJU international (2020)

This two-phase study identified three SNPs (rs12615669, rs4976845, and rs2989734) associated with aggressive NMIBC and one SNP (rs4976845) associated with a higher risk of progression.

Keyphrases

muscle invasive bladder cancer
genome wide
randomized controlled trial
dna methylation
open label
gene expression