In Vivo Study of the Inflammatory Tissue Response Surrounding a Novel Extended-Wear Kink-Resistant Insulin Infusion Set Prototype Compared With a Commercial Control Over Two Weeks of Wear Time.
Jasmin R KastnerGabriella EislerMarc C TorjmanAbdurizzagh KhalfDavid DiazAlek R DinesenChanny LoeumPaul J StrasmaJeffery I JosephPublished in: Journal of diabetes science and technology (2022)
The data suggest that the infusion set prototype elicits less inflammation over an extended wear time and is resistant to kinking, compared with a commercial Teflon device. This is consistent with previously published data on the impact of cannula material/angle on the inflammatory tissue response. We highlight the following important aspects of infusion set design: (1) secure skin adhesion, (2) reliable cannula insertion, (3) automatic removal of the stylet, (4) cannula material/design that resists kinking, and (5) minimization of local tissue inflammation.
Keyphrases
- oxidative stress
- low dose
- extracorporeal membrane oxygenation
- respiratory failure
- positive airway pressure
- type diabetes
- big data
- randomized controlled trial
- deep learning
- obstructive sleep apnea
- high resolution
- systematic review
- acute respiratory distress syndrome
- intensive care unit
- soft tissue
- data analysis
- metabolic syndrome
- cystic fibrosis
- insulin resistance
- artificial intelligence
- weight loss