Transference interpretation has always been regarded as very important to psychoanalytic practice. However, analysts differ on its centrality relative to other forms of intervention. This paper argues that transference interpretation as introduced by Freud and then taken up and developed by Klein ("transference interpretation proper") is, in fact, the only form of intervention that could bring about essentially analytic change. To understand why, a taxonomy of different forms of intervention commonly practiced within the analytic situation is presented, including interventions that relate to transference, but do not constitute transference interpretation proper. The latter kind is then described in detail. Next, the paper defines analytic change. It relies on a particular perspective on what it is to come to know psychic truth; one that sees such knowing as a lived state of mind, rather than a state of having knowledge about one's dynamics. This foundational Freudian perspective has been especially advanced through Klein's notion of phantasy. Given this view of analytic change it becomes clear that it can only be brought about through transference interpretation proper. The paper also addresses reasons why it seems especially difficult to embrace this view in contemporary psychoanalytic culture, while stressing how crucial it is to do so.