Physician's appraisal vs documented signs and symptoms in the interpretation of food challenge tests: The EuroPrevall birth cohort.
Linus B GrabenhenrichAndreas ReichDoreen McBrideAline SprikkelmanGraham RobertsKate E C GrimshawAlessandro G FiocchiPhotini Saxoni-PapageorgiouNikolaos G PapadopoulosAna FiandorSantiago QuirceMarek L KowalskiSigurveig T SigurdardottirRuta DubakieneJonathan O B HourihaneLeonard RosenfeldBodo NiggemannThomas KeilKirsten BeyerPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2017)
These differences suggest that the comparison of food challenge outcomes between centers is difficult despite common protocols and training. We recommend detailed symptom assessment and documentation as well as objective sign-based challenge outcome algorithms to assure accuracy and comparability of blinded food challenges. Training and supervision of staff conducting food challenges is a mandatory component of reliable outcome data.