MNS1 promotes hepatocarcinogenesis and metastasis via activating PI3K/AKT by translocating β-catenin and predicts poor prognosis.

Yong YiMin-Cheng YuPei-Yao FuGao LiuPei-Yun ZhouRuo-Yu GuanCheng ZhouBao-Ye SunShuang-Jian Qiu

Published in: Liver international : official journal of the International Association for the Study of the Liver (2021)

MNS1 promotes HCC growth and metastasis via activating PI3K/AKT signalling and may serve as an important prognostic biomarker as well as potential novel therapeutic target for HCC.

Keyphrases

pi k akt
signaling pathway
poor prognosis
cell proliferation
epithelial mesenchymal transition
long non coding rna
cell cycle arrest
cell death