Standardized Titration Protocol Reduces the Incidence of Paclitaxel Infusion-Related Hypersensitivity Reactions.

Kofi SefahKarolina A KilowskiSarah A GiffordAngela GroveJon ShafferBaylee BryanSarfraz Ahmad Robert W Holloway

Published in: JCO oncology practice (2023)

A standardized paclitaxel titration protocol was associated with a significant reduction in the rate of infusion-related hypersensitivity reactions in patients receiving their first and second infusions. A prospective randomized trial is needed to validate these observations.

Keyphrases

randomized controlled trial
drug induced
low dose
risk factors