Photoredox-Catalyzed Cascade of o- Hydroxyarylenaminones to Access 3-Aminated Chromones.
Zhi-Wei WangYu ZhengYu-En QianJian-Ping GuanWei-Dong LuChu-Ping YuanJun-An XiaoKai ChenHao-Yue XiangJun-An XiaoPublished in: The Journal of organic chemistry (2022)
Reported herein is a photoredox-catalyzed amination of o- hydroxyarylenaminones with tert -butyl ((perfluoropyridin-4-yl)oxy)carbamate, a versatile amidyl-radical precursor developed in our laboratory. This work establishes a new cascade pathway for the assembly of a range of 3-aminochromones under mild conditions. Downstream transformations of the obtained 3-aminochromones to construct diverse amino pyrimidines greatly broaden the applications of this photocatalyzed protocol.