Senolytic Intervention Improves Cognition, Metabolism, and Adiposity in Female APP NL-F/NL-F Mice.

Yimin Fang Mackenzie R PeckKathleen QuinnDavid MedinaStephen RoySamuel A McFadden Andrzej BartkeKevin N HascupErin R Hascup

Published in: bioRxiv : the preprint server for biology (2023)

Considering women have a greater risk of dementia, identifying senotherapeutics appropriate for sex and disease stage is necessary for personalized medicine.

Keyphrases

mild cognitive impairment
polycystic ovary syndrome
insulin resistance
randomized controlled trial
high fat diet induced
cognitive impairment
pregnancy outcomes
white matter
multiple sclerosis
metabolic syndrome
breast cancer risk
type diabetes
skeletal muscle
adipose tissue
wild type