Heterogeneity of Treatment Effects From an Intensive Lifestyle Weight Loss Intervention on Cardiovascular Events in Patients With Type 2 Diabetes: Data From the Look AHEAD Trial.
Tamar I de VriesJannick A N DorresteijnYolanda van der GraafFrank L J VisserenJan WesterinkPublished in: Diabetes care (2019)
This post hoc analysis of the Look AHEAD trial showed that an intensive lifestyle intervention aimed at weight loss may reduce cardiovascular events in selected patients but may have a detrimental treatment effect in others.
Keyphrases
- cardiovascular events
- weight loss
- cardiovascular disease
- coronary artery disease
- bariatric surgery
- randomized controlled trial
- clinical trial
- roux en y gastric bypass
- metabolic syndrome
- end stage renal disease
- study protocol
- newly diagnosed
- ejection fraction
- physical activity
- phase iii
- chronic kidney disease
- type diabetes
- single cell
- insulin resistance
- combination therapy
- glycemic control
- open label