The VEST External Support for Saphenous Vein Grafts in Coronary Surgery: A Review of Randomized Clinical Trials.
Giovanni Jr SolettiMichele Dell'AquilaLamia HarikGianmarco CancelliTalal AlzghariRoberto Perezgrovas-OlariaArnaldo DimagliKevin R AnJordan LeithCamilla Sofia RossiChristopher F BarileMichelle DemetresChristopher LauLeonard N GirardiMario F L GaudinoPublished in: Journal of cardiovascular development and disease (2023)
Saphenous vein grafts (SVGs) are the most frequently used conduits in coronary artery bypass grafting (CABG), but their higher rate of occlusion compared to arterial conduits remains a concern. Previous studies have shown that SVG failure is mainly driven by intimal hyperplasia, an adaptative response to higher pressures of the arterial circulation. The VEST TM device (Vascular Graft Solutions, Tel Aviv, Israel), an external support designed to mitigate intimal hyperplasia in SVGs, has been tested in few clinical trials (RCTs). Herein, we descriptively evaluated the randomized evidence on the VEST device.
Keyphrases
- coronary artery bypass grafting
- coronary artery bypass
- percutaneous coronary intervention
- coronary artery disease
- clinical trial
- double blind
- acute coronary syndrome
- phase ii
- open label
- phase iii
- placebo controlled
- coronary artery
- minimally invasive
- heart failure
- randomized controlled trial
- surgical site infection
- study protocol