Purified Cannabidiol for Treatment of Refractory Epilepsies in Pediatric Patients with Developmental and Epileptic Encephalopathy.

Nicola PietrafusaAlessandro FerrettiMarina TrivisanoLuca de PalmaCostanza CalabreseGiusy Carfì PaviaIlaria TondoSimona CappellettiFederico VigevanoNicola Specchio

Published in: Paediatric drugs (2019)

These data suggest that CBD may have beneficial effects in patients with DEE and an acceptable safety profile. Placebo-controlled randomized trials should be conducted to formally assess the safety and efficacy of CBD in patients with DEE.

Keyphrases

placebo controlled
double blind
early onset
electronic health record
big data
study protocol
squamous cell carcinoma
randomized controlled trial
clinical trial
phase ii
phase ii study
artificial intelligence
data analysis
open label