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Laboratory evaluation of immunochromatographic rapid diagnostic tests for cholera in Haiti.

Wilfredo R MatiasFabrice E JulceusCademil AbelardLeslie M Mayo-SmithMolly F FrankeJason B HarrisLouise C Ivers
Published in: PloS one (2017)
There is significant variation in the performance of different cholera diagnostic RDTs. Artron and Crystal VC RDTs have high sensitivity and low specificity, while SD Bioline RDT has low to moderate sensitivity and high specificity when performed by laboratory technicians in Haiti. Study limitations included its retrospective design. The suboptimal characteristics of these tests limit their use as clinical point-of-care tests; however, they may be useful in outbreak response, surveillance, and research in resource-limited settings.
Keyphrases
  • public health
  • cross sectional
  • structural basis
  • loop mediated isothermal amplification