Not all moderate disease is the same - Identification of disability trajectories among patients with rheumatoid arthritis and moderate disease activity.
Yi PanSam NortonJames Martin GwinnuttLianne Kearsley-FleetDeborah P M SymmonsMark LuntAdam Youngnull nullKimme L HyrichSuzanne M M VerstappenPublished in: PloS one (2019)
There is substantial heterogeneity in baseline HAQ scores in this population, and the trajectories of HAQ scores after baseline are, on average, relatively flat. As bDMARD therapy has been shown to improve HAQ scores, patients with MDA but high HAQ scores may benefit from a more aggressive approach to therapy.