Statistical learning quantifies transposable element-mediated cis-regulation.
Cyril PulverDelphine GrunJulien DucShaoline SheppardEvarist PlanetAlexandre CoudrayRaphaël de FondevilleJulien PontisDidier TronoPublished in: Genome biology (2023)
Our results suggest that TE-embedded CREs contribute to gene regulation during and beyond gastrulation. On a methodological level, we provide a statistical tool that infers TE-dependent cis-regulation from RNA-seq data alone, thus facilitating the study of TEs in the next-generation sequencing era.