Renal expression of cytokines and chemokines in diabetic nephropathy.

Liliane Silvano AraújoBianca Gonçalves Silva TorquatoCrislaine Aparecida da SilvaMaria Luíza Gonçalves Dos Reis MonteiroAna Luisa Monteiro Dos Santos MartinsMarcos Vinícius da SilvaMarlene Antônia Dos ReisJuliana Reis Machado

Published in: BMC nephrology (2020)

Our results indicated an increased in situ production of cytokines and chemokines in DN, including IL-6, IL-1β, IL-4, and eotaxin. It was observed that, possibly, eotaxin may have an important role in the progression of interstitial inflammation in DN and in eGFR decrease of these patients.

Keyphrases

diabetic nephropathy
end stage renal disease
small cell lung cancer
ejection fraction
poor prognosis
oxidative stress
chronic kidney disease
peritoneal dialysis
prognostic factors
tyrosine kinase
long non coding rna
patient reported