Efficacy and safety of nivolumab monotherapy in patients with unresectable clear cell sarcoma and alveolar soft part sarcoma (OSCAR Trial/NCCH1510).

Tadaaki Nishikawa Shigeki KakunagaKenji TamuraMasashi AndoToshiyoshi Fujiwara Akira Kawai Takafumi Ueda Mamiko Kawasaki Sawako TomatsuriNobuko OkamuraMasahisa Kamikura Akinobu Hamada Akihiko Yoshida Akihiro HirakawaTaro ShibataKenichi Nakamura Kan Yonemori

Published in: Cancer (2024)

The primary end point of the ORR was not met for CCS and ASPS on the central review. Further studies are needed to evaluate ICIs in patients with ASPS.

Keyphrases

clear cell
phase iii
study protocol
open label
clinical trial
phase ii
tyrosine kinase
combination therapy
locally advanced
case control
randomized controlled trial
squamous cell carcinoma
radiation therapy
placebo controlled