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Clusters of Disease Activity and Early Risk Factors of Clinical Course of Pediatric Crohn's Disease.

Manuela DistanteSilvia RotuloMarco RanalliEugenio PedacePaolo LionettiSerena ArrigoPatrizia AlvisiErasmo MieleMassimo MartinelliGiovanna ZuinMatteo BramuzzoMara CananziMarina Aloinull null
Published in: Inflammatory bowel diseases (2023)
During the first 5 years of follow-up, one-third of children with CD experience a quiescent course. However, another one-third have a moderate-to-severe disease course. Surgery at the diagnosis is related to a quiescent course, while growth impairment and lack of response to induction therapy correlate with more severe disease activity during follow-up.
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