The zinc finger and BTB domain containing protein ZBTB20 regulates plasma triglyceride metabolism by repressing lipoprotein lipase gene transcription in hepatocytes.

Hao LiGan LiuXiaoqing WanLuting ZhouZhen-Bang QinXian-Hua MaKai SuYa-Jin LiuJinghao YuanChun-Chun WeiAn-Jing RenYu-Xia ChenStephen G YoungHai ZhangZhifang XieWeiping J Zhang

Published in: Hepatology (Baltimore, Md.) (2021)

Liver ZBTB20 serves as a key regulator of LPL expression and plasma triglyceride metabolism and could be a therapeutic target for hypertriglyceridemia.

Keyphrases

low density lipoprotein
poor prognosis
transcription factor
binding protein
copy number
genome wide
liver injury
protein protein
small molecule
long non coding rna
drug induced