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Efficacy and safety of evogliptin treatment in patients with type 2 diabetes: A multicentre, active-controlled, randomized, double-blind study with open-label extension (the EVERGREEN study).

Sang-Man JinSoo LimHyuk-Sang KwonIe B ParkKyu J AhnCheol-Young ParkSu K KwonHye S KimSeok W ParkSin Gon KimMin Kyong MoonEun S KimChoon Hee ChungKang S ParkMikyung KimDong J ChungChang B LeeTae H KimMoon-Kyu Lee
Published in: Diabetes, obesity & metabolism (2020)
In this study, the glucose-lowering efficacy of evogliptin was non-inferior to linagliptin. It was maintained at week 24 with a 0.94% reduction in HbA1c. Evogliptin therapy improved glycaemic variability without causing any serious adverse events in patients with type 2 diabetes.
Keyphrases
  • double blind
  • open label
  • clinical trial
  • placebo controlled
  • phase iii
  • squamous cell carcinoma
  • randomized controlled trial
  • phase ii
  • insulin resistance
  • phase ii study
  • smoking cessation
  • replacement therapy