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Ten-year prediction model for post-bronchodilator airflow obstruction and early detection of COPD: development and validation in two middle-aged population-based cohorts.

Jennifer L PerretDon VicendeseKoen SimonsDebbie L JarvisAdrian J LoweCaroline J LodgeDinh S BuiDaniel TanJohn A BurgessBircan ErbasAdrian BickerstaffeKerry HancockBruce R ThompsonGarun S HamiltonRobert AdamsGeza P BenkePaul S ThomasPeter A FrithChristine F McDonaldTony BlakelyMichael John AbramsonE Haydn WaltersCosetta MinelliShyamali C Dharmagenull null
Published in: BMJ open respiratory research (2021)
This novel and validated risk-prediction model could identify adults aged in their 40s at high 10-year COPD-risk in the general population with potential to facilitate active monitoring/intervention in predicted 'COPD cases' at a much earlier age.
Keyphrases
  • chronic obstructive pulmonary disease
  • lung function
  • middle aged
  • randomized controlled trial
  • cystic fibrosis
  • risk assessment
  • air pollution
  • human health