Efficacy of Lidocaine Infusion in High-Risk Vascular Surgery-A Randomized, Double-Blind, Placebo-Controlled Single-Center Clinical Trial.
Dariusz GajniakKonrad MendralaTomasz CyzowskiMichał PolakDanuta GierekŁukasz Jerzy KrzychPublished in: Journal of clinical medicine (2023)
In high-risk vascular surgery, lidocaine infusion as an adjunct to standard perioperative analgesia is effective. It may decrease opioid consumption by more than 20% during the first 24 h after surgery, with no serious adverse effects noted during the study period.
Keyphrases
- double blind
- placebo controlled
- clinical trial
- minimally invasive
- coronary artery bypass
- phase ii
- phase iii
- pain management
- study protocol
- low dose
- surgical site infection
- patients undergoing
- randomized controlled trial
- open label
- radiation therapy
- cardiac surgery
- phase ii study
- coronary artery disease
- acute kidney injury
- percutaneous coronary intervention
- postoperative pain
- acute coronary syndrome