CDH1 overexpression sensitizes TRAIL resistant breast cancer cells towards rhTRAIL induced apoptosis.

Poulami TapadarAmbika PalNirajan GhosalBhupender KumarTamalika PaulNabendu BiswasRanjana Pal

Published in: Molecular biology reports (2023)

CDH1 overexpression sensitizes TR cells towards rhTRAIL induced apoptosis. Therefore, we can hypothesize that CDH1 expression should be taken into account while performing TRAIL therapy in breast cancer.

Keyphrases

induced apoptosis
endoplasmic reticulum stress
signaling pathway
breast cancer cells
oxidative stress
cell proliferation
poor prognosis
transcription factor
binding protein
pi k akt
stem cells
young adults
mesenchymal stem cells
cell death
breast cancer risk
cell cycle arrest