Bias and sample size in intensive care unit trials: Protocol for a meta-epidemiological study.

Carl Thomas Anthon Anders Granholm Anders Perner Jon Henrik Laake Morten Hylander Möller

Published in: Acta anaesthesiologica Scandinavica (2018)

The outlined meta-epidemiologic study will assess time trends in risk of bias and sample sizes in RCTs assessing ICU interventions. This will inform researchers, healthcare personnel and policymakers on the general reliability of findings from RCTs of ICU interventions over time, and inform future RCT design and reporting.

Keyphrases

intensive care unit
healthcare
mechanical ventilation
physical activity
randomized controlled trial
emergency department
acute respiratory distress syndrome
extracorporeal membrane oxygenation