Familial abnormalities of endocannabinoid signaling in schizophrenia.

Dagmar Koethe Franziska Pahlisch Martin Gunnar Hellmich Cathrin RohlederJuliane K MuellerAndreas Meyer-LindenbergE Fuller TorreyDaniele Piomelli F Markus Leweke

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2018)

We suggest that the protective upregulation of endocannabinoid signalling reflects either a hereditary trait or mirrors a modulating response to genetically influenced cerebral function involving, e.g., other neurotransmitters or energy metabolism.

Keyphrases

signaling pathway
bipolar disorder
subarachnoid hemorrhage
poor prognosis
early onset
cell proliferation
genome wide
brain injury
cerebral ischemia
blood brain barrier