Resilience, mental health, sleep, and smoking mediate pathways between lifetime stressors and Multiple Sclerosis severity.

Carri S PolickHala DarwishLeo Pestillo de OliveraAli WatsonJoao Ricardo Nickenig VissociPatrick S CalhounRobert Ploutz-SnyderCathleen M ConnellTiffany J BraleySarah A Stoddard

Published in: medRxiv : the preprint server for health sciences (2024)

Lifetime stressors directly and indirectly relate to MS severity.Resilience, mental health, sleep, and smoking were mediators.Resilience attenuated the effects of stressors on mental health, sleep, and smoking.Multi-modal interventions are needed to help improve MS symptom severity.

Keyphrases

mental health
multiple sclerosis
physical activity
smoking cessation
climate change
sleep quality
mass spectrometry
social support
mental illness
ms ms
patient reported