MAT2A inhibition suppresses inflammation in Porphyromonas gingivalis -infected human gingival fibroblasts.

Lishan JiangJingwen LiKun JiLang LeiHouxuan Li

Published in: Journal of oral microbiology (2023)

MAT2A-mediated methionine metabolism promoted P. gingivalis-inducedinflammation in hGFs. Targeting MAT2A may provide a novel therapeuticmethod for modulating periodontitis.

Keyphrases

signaling pathway
endothelial cells
oxidative stress
induced pluripotent stem cells
pluripotent stem cells
extracellular matrix