Racial and ethnic differences in the association between depressive symptoms and cognitive outcomes in older adults: Findings from KHANDLE and STAR.
Marcia P JimenezEmma L GauseKendra D SimsEleanor Hayes-LarsonEmily P MorrisEvan FletcherJennifer ManlyPaola GilsanzYenee SohMaria CorradaRachel A WhitmerMedellena Maria GlymourPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
We examined whether baseline depressive symptoms were differentially associated with domain-specific cognition or cognitive decline by race/ethnicity. Depressive symptoms were associated with worse cognitive scores for all racial/ethnic groups across different domains examined. Higher depressive symptoms were associated with faster cognitive decline for semantic memory for Black and Latino participants. The results suggest a particularly harmful association between depressive symptoms and cognition in certain racial/ethnic groups.