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Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.

Xianzhong XuSurya V S R K PulavartiAlexander EletskyYuanpeng Janet HuangThomas B ActonRong XiaoJohn K EverettGaetano T MontelioneThomas Szyperski
Published in: Journal of structural and functional genomics (2014)
High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved. These domains were chosen as targets of a biomedical theme project pursued by the Northeast Structural Genomics Consortium. This project focuses on increasing the structural coverage of human proteins associated with cancer.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • high resolution
  • pluripotent stem cells
  • magnetic resonance
  • papillary thyroid
  • transcription factor
  • squamous cell carcinoma
  • solid state
  • squamous cell