Role of Vitamin E for Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes: A Randomized Controlled Trial.

Fernando BrilDiane M BiernackiSrilaxmi KalavalapalliRomina LomonacoSreevidya K SubbarayanJinping LaiFermin TioAmitabh SumanBeverly K OrsakJoan HechtKenneth Cusi

Published in: Diabetes care (2019)

In this proof-of-concept study, combination therapy was better than placebo in improving liver histology in patients with NASH and T2DM. Vitamin E alone did not significantly change the primary histological outcome.

Keyphrases

combination therapy
double blind
phase iii
randomized controlled trial
clinical trial
type diabetes
adipose tissue
metabolic syndrome
placebo controlled
skeletal muscle
insulin resistance
weight loss
study protocol