Spatiotemporal ATF3 Expression Determines VSMC Fate in Abdominal Aortic Aneurysm.

Ying Wen Yingying LiuQiang LiJinlin TanXing Fu Yiwen LiangYonghua TuoLuhao LiuXueqiong ZhouDongkai LiuFuXuejiao FanChaofei ChenZheng ChenZhouping WangShunyang FanRenjing LiuLei PanYuan Zhang Wai Ho Tang

Published in: Circulation research (2024)

Our results demonstrate a previously unrecognized role of ATF3 in AAA development and progression, and ATF3 may serve as a novel therapeutic and prognostic marker for AAA.

Keyphrases

abdominal aortic aneurysm
endoplasmic reticulum stress
transcription factor
poor prognosis
binding protein
long non coding rna