Testosterone treatment, weight loss and health-related quality of life and psychosocial function in men: a two-year RCT.
Mathis GrossmannKristy P RobledoMark DanielDavid J HandelsmanWarrick J InderBronwyn G A StuckeyBu B YeapMark Ng Tang FuiKaren BrackenCarolyn A AllanDavid JesudasonJeffrey D ZajacGary Allen WittertPublished in: The Journal of clinical endocrinology and metabolism (2024)
In this diabetes prevention trial, weight loss induced by a lifestyle intervention improved HR-QOL and psychosocial function in more domains than testosterone treatment. The magnitude of weight and waist circumference reduction were predicted by baseline physical function, depressive symptomology, and sense of coherence.
Keyphrases
- weight loss
- body mass index
- bariatric surgery
- roux en y gastric bypass
- replacement therapy
- type diabetes
- cardiovascular disease
- randomized controlled trial
- gastric bypass
- glycemic control
- physical activity
- body weight
- metabolic syndrome
- clinical trial
- study protocol
- bipolar disorder
- combination therapy
- obese patients
- adipose tissue
- stress induced
- skeletal muscle