Sinus Node Dysfunction and Pulmonary Hypertension-"Double Trouble" with Lithium Therapy.
Shweta VohraAkshyaya PradhanRishi SethiMonika BhandariPublished in: The International journal of angiology : official publication of the International College of Angiology, Inc (2021)
Lithium is considered a gold standard drug for the management of bipolar disorder and is a widely used mood-stabilizing drug in psychiatry practice. However, its side effects are of important concern. The narrow therapeutic index of lithium predispose to its toxicity/side effects, but various case reports and research has shown that adverse drug reactions can occur even in the therapeutic range. We present the case of a 56-year-old woman with no history of cardiac illness presenting with tachycardia-bradycardia syndrome along with moderate pulmonary hypertension. Patients recovered to sinus rhythm after withholding lithium therapy for 1 week while her mean pulmonary artery pressure remained the same at day 10 of drug withdrawal.
Keyphrases
- pulmonary hypertension
- pulmonary artery
- adverse drug
- bipolar disorder
- pulmonary arterial hypertension
- coronary artery
- solid state
- case report
- end stage renal disease
- oxidative stress
- major depressive disorder
- chronic kidney disease
- newly diagnosed
- ejection fraction
- emergency department
- electronic health record
- drug induced
- primary care
- healthcare
- lymph node
- prognostic factors
- randomized controlled trial
- stem cells
- high intensity
- peritoneal dialysis
- clinical trial
- quality improvement