Amide-Directed C-H Sodiation by a Sodium Hydride/Iodide Composite.

Yinhua HuangGuo Hao ChanShunsuke Chiba

Published in: Angewandte Chemie (International ed. in English) (2017)

A new protocol for amide-directed ortho and lateral C-H sodiation is enabled by sodium hydride (NaH) in the presence of either sodium iodide (NaI) or lithium iodide (LiI). The transient organosodium intermediates could be transformed into functionalized aromatic compounds.

Keyphrases

randomized controlled trial
minimally invasive
quantum dots
mass spectrometry
cerebral ischemia
brain injury
liquid chromatography