The conceptualization of resilience following acquired brain injury needs to remain sensitive to the complex nature and enduring dimensions of trauma, loss, and stress. It is essential that a systemic and dynamic view be maintained with a focus on the key adaptation tasks that families face: grieving, restructuring, identity redefinition, and growing through adversity. These tasks are explored in a case example illustrating how these challenges reemerge across the life cycle. The key theme in this contribution is that resilience is a fluid property, a potential that practitioners and service systems can listen for, support, strengthen, and hold in trust.