A systematic review of interleukin-31 inhibitors in the treatment of prurigo nodularis.

Mohammad Ali Nilforooshzadeh Nazila Heidari Yekta Ghane Amirhossein Heidari Arman Hajikarim-Hamedani Seyedayin Hosseini Fariba Jaffary Minou Najar Nobari Pegah Tavakolzadeh Niloufar Najar Nobari

Published in: Inflammopharmacology (2024)

IL-31 inhibitors suggest distinct advantages in improving pruritus, sleep quality, and overall quality of life in subjects with moderate-to-severe PN. Further clinical studies are recommended to compare the effectiveness of these biologics to other therapeutic choices.

Keyphrases

sleep quality
depressive symptoms
randomized controlled trial
systematic review
high intensity