Retinoic acid signaling regulates Krt5 and Krt14 independently of stem cell markers in submandibular salivary gland epithelium.

Timur M AbashevMelissa A MetzlerDiana M WrightLisa L Sandell

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2018)

RA regulates Krt5 and Krt14 expression independently of stem cell character in developing salivary epithelium. RA, or chemical inhibitors of RA signaling, could potentially be used for modulating growth and differentiation of epithelial stem cells for the purpose of re-populating damaged glands or generating bioengineered organs. Developmental Dynamics 246:135-147, 2017. © 2016 Wiley Periodicals, Inc.

Keyphrases

stem cells
rheumatoid arthritis
disease activity
ankylosing spondylitis
poor prognosis
cell therapy
signaling pathway
interstitial lung disease
systemic lupus erythematosus
mesenchymal stem cells
bone marrow