Efficacy and toxicity of bimodal radiotherapy in WHO grade 2 meningiomas following subtotal resection with carbon ion boost: prospective phase 2 MARCIE trial.
Maximilian Y DengSybren L N MaasFelix HinzChristian P KargerPhilipp SieversTanja EichkornEva MeixnerPhilipp Hoegen-SassmannshausenJuliane Hörner-RieberJonathan W LischalkKatharina SeidensaalDenise BernhardtChristine JungkAndreas UnterbergAntje WickWolfgang WickAndreas von DeimlingFelix SahmStephanie CombsKlaus HerfarthJürgen DebusLaila KönigPublished in: Neuro-oncology (2023)
Our study demonstrates a bimodal approach utilizing photons with C12-boost may achieve an superior local PFS to conventional photon RT, but must be balanced against the potential risks of toxicities.