The placebo effect in randomized-controlled trials of medical treatments for chronic rhinosinusitis: A systematic review and meta-analysis.

Royal M PipaliyaKelsey A DuckettNeil P MonaghanEmma Marin MillerGabrielle YoungEmily A BrennanShaun A NguyenZachary M SolerRodney J Schlosser

Published in: International forum of allergy & rhinology (2023)

Placebo treatments have a statistically and potentially clinically significant effect on patient-reported and some objective CRS outcomes. Further investigation is required to fully understand placebo effect, which could improve assessment of RCTs and impact patient care.

Keyphrases

patient reported
randomized controlled trial
type diabetes
chronic rhinosinusitis
double blind
skeletal muscle
insulin resistance
clinical evaluation