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Evaluation of medullary cytokine expression and clinical and laboratory aspects in severe human visceral leishmaniasis.

Leandro de Freitas TelesAgostinho Gonçalves VianaMariana Santos CardosoGuilherme Rafael Gomide PinheiroGabriele Ariadine BentoJamille Fernandes LulaTânia de Cássia Moreira SoaresRicardo Toshio FujiwaraSilvio Fernando Guimarães de Carvalho
Published in: Parasite immunology (2021)
This study demonstrates that VL stimulates an non-dichotomized inflammatory response between Th1/Th2 and that bone marrow is an important tissue for immune regulation.
Keyphrases
  • inflammatory response
  • bone marrow
  • endothelial cells
  • poor prognosis
  • mesenchymal stem cells
  • lipopolysaccharide induced
  • early onset
  • lps induced
  • toll like receptor
  • immune response