Traumatic brain injury does not disrupt costimulatory blockade-induced immunological tolerance to glial-restricted progenitor allografts.

Rui WangChengyan ChuZhiliang WeiLin ChenJiadi XuYajie LiangMiroslaw JanowskiRobert D StevensPiotr Walczak

Published in: Journal of neuroinflammation (2021)

CoB induces sustained immunological tolerance towards allografted cerebral GRPs which is not disrupted following TBI, and unexpectedly TBI may enhance GRPs engraftment and contribute to post-injury brain tissue repair.

Keyphrases

traumatic brain injury
resting state
severe traumatic brain injury
functional connectivity
cerebral ischemia
high glucose
diabetic rats
subarachnoid hemorrhage
white matter
drug induced
oxidative stress
neuropathic pain
mild traumatic brain injury